customize .mxd layout programmatically using .NET?

[JosephSaltenberger]

Is there a way to customize the the layout for an .mxd programmatically in .NET (i.e. turning off certain toolbars, menus, etc...) when the .mxd is opened?

I have been successful in saving layout settings to the .mxd within ArcMap, and was wondering if there is a way to do this through .NET

Thanks.

[DuncanHornby]

If you want to manipulate tool bars then this can be achieved by using the Interface ICommandbars, ICommandBar and ICommandItem interfaces.