In Arc Catalog (10.5.1), when right-clicking on a SDE geodatabase connection, selecting properties, connection tab, show connected users, one can select ALL of the connections and right-click -> Disconnect.
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In Pro 2.1, same steps, however once you right-click (after selecting all of the connections), the selection is lost and you are only able to disconnect whatever connection the mouse pointer happened to be over.
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Forcing disconnects is an essential part of enterprise geodatabase administration. Many of my geodatabases can have dozens of connections. Having to right click on them one by one.....