We're about to roll out our first mobile Javascript application based on the Find Nearby location example, which uses dojox mobile. It worked better on mobile devices that it did in the older browsers we have installed (IE7, IE8). I felt like I needed it to work in our browsers too, not just on mobile. The first thing people will do when you send out a notice of a new map is to try it out (no matter what device they happen to be using at the time!). I spent a fair amount of time debugging for IE and I ended up having to use a slightly older version of the Javascript library, which ended up working better for IE (used version 2.8).
Even though the example is written calling the iPhone CSS, it has been tested successfully on an Android, Windows Phone and Blackberry too. I don't know about Sencha touch.