Generally, one field with type 'text' (PDF) in the table should be added, saying 'hotlink'. Here, you should make sure that the length of the field is enough for your (IP - or http-dependent) hyperlink across your organization.
Then, you can edit and add your hyperlinks to the features.
Finally, users can view via Identity or others, and open those hyperlinks in IE by right-click in desktop ArcGIS, when needed.
In practice, for flexibility, it is better to create a separate feature class in a File GDB, and then join with your Mosaic Dataset, as long as both share same unique field.
For more, you can open PDF attached.