Original User: gsumerling
As a follow-up to Melanie's comments, at 10.1 you will be able to cache an Image Service directly with ArcGIS Server.
However, before you go ahead and cache an Image Service/Mosaic Data set it is important that you consider what advantages it gives you. An image service based on a Mosaic dataset is already quite fast. It returns what you need at the extents you need it. If you cache an image service you effectly double the amount of diskspace required to store the images. Once for the image source and once for the Cache. Do you have this amount of space available. Finally, how much more speed will the cache of an image service give me. In most cases between 5 and 10%. Will your end users notice this extra speed and is it worth the extra disk capacity required?
Hope this helps you with your caching strategies
Cheers
Gordon