I get multiple "Drawing Alert: General Function Failure" messages every day. And if the affected layer is one I am currently working on then it doesn't show on the map, and I can't save any edits I have made.
Closing and reopening Pro solves the error, but sometimes it's only 10 minutes before it happens again.
I found a post for ArcMap, but it doesn't really get into the root cause and how to fix it.
ArcMap Drawing Error: General Function Failure - Esri Community