We just recently upgraded to 10.2.2 from 10.0 SP5 - Desktop upgrade only. SDE and the database remain at 10.0 SP5.
Once we upgraded the desktop software, we began seeing the below error message whenever solving a network analyst route. I've tried exporting the network to a 10.2.2 file geodatabase and running the Upgrade Dataset tool without success. There have been no schema changes to the dataset, and the route still solves using 10.0 SP5 software.