You could modify the MaxPS in the service table of the ISDef to something larger, so it will get displayed as smaller scales.
I'm assuming you have a collection of raster datasets in the ISDef.
If you publish just one raster dataset (as it looks like you're suggesting), then you do not need to create an ISDef. You can just publish that raster dataset as an image service--note, you will no longer have any mosaic methods to choose as they're not needed. Be sure to create pyramids as this will help it display faster at smaller scales.