I have installed 32 and 64 bit Oracle Instant Client 11.2 with the 64bit patch first in line. ArcGIS Desktop is working fine, but ArcGIS Pro Prerelease has the following error.
Connection Error Failed to connect to specified server. A database connection exception has occurred. Cannot connect to database because the database client software failed to load. Be sure the database software is installed and configured correctly.
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We are getting both to work without changing the path statement.
No, you do not need to switch between the 32-bit and 64-bit clients to be first in the path, to use Desktop (32-bit) and ArcGIS Pro (64-bit) on the same machine.
You just need to ensure that the 64 bit client is listed first in the path variable and then the 32-bit client is listed.