What is the question?
I download a App. from the internet,open it with 10.1 and it shows the error when running:
Could not load file or assembly 'ESRI.ArcGIS.ADF.Local, Version=10.0.0.0, Culture=neutral, PublicKeyToken=8fc3cc631e44ad86' or one of its dependencies. The system cannot find the file specified
I have load the "version,ADF assembly" and all of the .dll assembly property(Specified Verson) is not set to "True".
Of course I have install the SDK,even the Engine.