We are beginning several new developments in .NET, we would like to use Visual Studio 2015 and the .NET Framework 4.5.
Can we safely use the ArcObjects SDK 10.4 with our ArcGIS 10.3 servers, which are not due to be upgraded until after our development cycle.
10.3 server requirements
net requirements
System requirements—ArcGIS Runtime SDK for .NET | ArcGIS for Developers
but you are going to have to comfirm your pairing with like pages in the server an sdk sections to see if everything matches