Hi Curtis Price,
Yes and no and sort of.
I keep a separate Conda env for GDAL stuff and (conda create -n some_new_env -c conda-forge python=3.5 gdal) and keep my ArcGIS Pro env pristine (well pristine so far... )
I had some trouble with the old version of conda that ships with ArcGIS Pro 1.3 as it wouldn't run the GDAL pre and post activation batch files (that set and restore some environment vars). So I upgraded conda, broke ArcGIS Pro completely and had to reinstall... I then ended up installing a separate updated conda to muck around with and leaving ArcGIS Pro completely alone.