Working with NetCDF can be challenging and require investing in either tooling or data manipulation skills to get what you want, especially if you are working with specific models that store their data in ways less aligned with the more traditional data representations. The Pro Python distribution includes both netcdf4 and xarray which can work with NetCDF files directly, see for example this user who shifted values with netcdf4. The xarray package has a number of reshaping operations including "roll" functions which can be used to shift the data as well. I would recommend you start small with a specific dataset, in practice it will take some learning before you can easily manipulate arbitrary NetCDF files if they differ in structure.
Cheers, Shaun
