Change the map object in a mapframe

[FCC_EnvironmentS_A_]

Dear ESRI community. I need help.
I have a layout with 6 maps (map series). A map for each day of the week (Monday to Saturday). Each map represents a day's work cleaning the streets. When you don't work in a day, the map shouldn't be seen.

In other words when the layer is not visible on the map extent the map object of the map frame must be null.

How can I do this with python?

?