There is ... still ... confusion regarding the proper use of the Define Projection Tool versus the Project Tool.

"my data don't line up..."
"I am sure about the coordinate system..."
"everything is far apart onscreen..."
We have all been there. The written descriptions don't seem to catch on, so a visual guide might be what is needed.
Prior to proceeding... make sure you have seen the ...References... at the end of this section... that is what you need to understand.
So with tongue firmly planted in cheek...
The choice really depends on:
- what you know you have... not what you think you have...
- what you really need...
- applying the correct tool... if it doesn't work out, undo what you did... locate the originals... read the metadata
- understanding what you got and why.
References
And to cover some of the other combinations and permutations, just remember....things can get worse, before they get better...
