"We do run maintenance Monday – Thursday with a script that blocks connections, disconnects users, reconciles the versions, compresses the database then finally opens the connections. We don’t run that script over the weekend, so what would cause the box to be unchecked/blocking connections?"
I would start by checking if the "script" is really running only on the indicated days and or someone else is running another script on a different day, you can also change the sde user password, and create a new gdb connection file, and share it with only the people that really need it, this way you limit the number of people and scripts that can make any changes to your enterprise geodatabase connected as the sde user.
Note, Oracle DBA can turn auditing on to capture changes to a particular table, in this case the sde.server_config table that stores the option to disable geodatabase connections, this way you might be able to track who is making the change.
I hope this helps.
| Marcelo Marques | Esri Principal Product Engineer | Cloud & Database Administrator | OCP - Oracle Database Certified Professional | "In 1992, I embarked on my journey with Esri Technology, and since 1997, I have been working with ArcSDE Geodatabases, right from its initial release. Over the past 32 years, my passion for GIS has only grown stronger." | “ I do not fear computers. I fear the lack of them." Isaac Isimov |