Hi Jeff,
Yes, I do use the recommended skip factor of 1000. I have tried estimating statistics since the MrSID rasters already have them and I do not want to recreate them.
What is confusing me is that all of the statistics tools will run, but statistics do not get populated into the properties. I just ran a color balance using dodging 3rd order on a mosaic dataset containing 11 mosaic datasets each holding 1 MrSID raster. All of the original rasters have statistics and histograms calculated. I realize that I should be able to add all 11 MrSID rasters into the same mosaic dataset, but I started with that method and am working on isolating the issue.
The color balance did not change the image, and their is not a color balance to remove from the mosaic dataset. I did not receive any warnings or errors about statistics not being calculated when the color balance tool ran.
Also, when I run the analyze mosaic dataset tool, there are no messages about statistics not calculated.
There seems to be something fishy with the compression. Maybe bad source data during download. I would just hate to have to re-download the images and have the same problem.