Yes, any layer in a CAD file can be extracted and moved into the Geodatabase and the entire process is repeatable and can be automated via Geoprocessing. Here are my scripts that accomplish the task of importing layers of a CAD file and converting to GIS features.
Eric J. Rodenberg | Solution Engineer Transportation Practice
Esri | 7775 Walton Pkwy, Suite 270 | New Albany, Ohio 43054-8202 | USA
T 614-933-8698, ext. 5503 | erodenberg@esri.com | esri.com