Removing duplicates label based on feature

[pramodmishra]

I have seen few posts here that shows you how to remove duplicate labels by adding new field. Also saw posts that talks about using Maplex tools that will remove duplicate values based on the buffer. So my question is removing the duplicates values based on feature not with distance how Maplex does. I think this can be achieved by using python coding in label expression. Please see the image below what I am trying to achieve.