Generally it is not a recommended practice to use special characters in a field/column name. The names should give an indication of what data is contained in that particular column.
Below would be a few web links for your reference:
FAQ: What characters should not be used in ArcGIS for field names and table names?
Thanks. The geodatabase already has feature classes in it set up with column names that start with #. This was done a while back before i got here. Now i will be designing a web application using the tables with column names that start with the #. I was worried it might make queries act strange?
You might want to clean up your data now (take the pain) and remove the # signs before you get deep into building/configuring your web applications where it might become much more difficult (painful) to clean your data with dependent apps hanging off non Best Practice data sets.