Hi Michael, I work in the IT department of a US County, for some background. Right now, we just have our power users in the departments using Pro, so just a small handful. Most people use a web application to view layers. For those who use ArcMap, the issue is getting them better, 64 bit PCs to be able to run Pro. In regard to our workflows, we need it to be able to work with the Parcel Fabric, but other than that, after lots of practice, I've gotten used to using it. Not sure about other departmental workflows. We are working on implementing Portal, though it's already great how it interacts with ArcGIS Online. Let me know if you have any specific questions.