I've recently upgraded to ArcPro v3.0 and I'm having a terrible experience any time interact with a FGDB or SDE (which is pretty much all the time!)
Any attempt to make or delete a FGDB, or connect to an Enterprise SDE (ArcGIS Server/SQL) my machine stalls. I've been able to produce a test in ArcNotebook that shows Pro 3 taking almost 2hrs to "open connection" before completing a 1min Reconcile & Post operation. While the machine is spinning, ExcelToSQLLite64 is visible in Task Manager "working" but apparently accomplishing very little. I've also noticed that upgraded v2.x aprx will hang entirely, never complete. Native v3.0 aprx do eventually complete after the 2hr+ hang.
Has anyone successfully replaced to updated ExcelToSQLLite64 to a working state? Quite a few threads are starting to accumulate related to this exe/dll:
ExcelToSQLite64 won't die (it's back) - Esri Community
ExcelToSQLite64 has stoppped working - pop ups - Esri Community
As well as several others, as far back at v2.6
@RaynahKamau