ArcGIS Pro 2.2.3 strange behaviour when opening aprx

[AlessandroValra]

Don't know if it's just me, if it was the last Windows update (I'm on 10) or the Planet lineup, but I've noticed since the last patch install (2.2.3), that my aprx don't open properly anymore.

By this, I mean that a porject suposed to open with a nice MapFrame will open with a grey area in the middle instead and no list in the Catalog Pane, resulting in the impossibility to access any folder, database, or whatever. All the tabs in thr ribbon are "unclickable".

Second thing: if from that "ghost" aprx I try to (re)open the same project, it opens displaying things correctly, except that again I cannot access the tabs in the ribbon.

Third strange thing: I have to type my AGOL password twice to open Pro EVERYTIME, although the password inserted was correct (I confirmed this by copying and pasting).

Has anybody else have noticed the same thinkg after upgrading? Anyway, I think it's time for a repair I guess...

[Robert_LeClair]

Hmmmm...I have not seen this behavior when I upgraded AGP from 2.2.2 to 2.2.3.  One workflow I use to correct strange AGP behaviors to rename the Esri folder in your C:\Users\<user profile>\AppData\Roaming and C:\Users\<user profile>\AppData\Local directories.  Does the behavior persist?

[DanPatterson_Retired]

No issues either, but there were 2 windows updates yesterday, but only one listed in history, so I suspect one was to 'fix' something in the first.  

Is all good now?  If not, rename your profile to see if a new one fixes things.

[AlessandroValra]

Thank you both for the hint, will try that if the error occur again. Will let you know.

[AlessandroValra]

No, apparently it is working fine now. Cannot tell if I had two consecutive Windows updates as you, but in case I'll see the strange behaviour again, I'll try yours and Robert LeClair‌ suggestions. Thank you both.