When attempting to recalculate spatial indexes within properties for a feature class in Pro, all of the buttons (recalculate, create, validate) are disabled. There is no indication as to why they are not available. The user is an administrator. The feature layers are included in a feature service, but the buttons are disabled even when the service is stopped.
The Rebuild Indexes tool fails as well with the non-helpful message 'Function had no effect'.
ArcGIS Pro 3.5.3 and ArcGIS Enterprise 11.x