A windows security update in November 2020 corrupted a file in Portal in one directory. There was no indication of a date change, but the file was almost blank.
C:\Program Files\ArcGIS\Portal\framework\runtime\tomcat\conf
Just in case someone else encounters weird errors. We have no idea why but rolling back the directory to a backup fixed it.
ESRI tech support knew about this possibility although it is not documented anywhere.
Has anyone else had this happen?