Hi Team,
We are currently facing an issue with slow response times in our multi-machine deployment of ArcGIS Enterprise 11.4. This poor / slow performance is noticeable when accessing the portal, performing various activities on it, or using ArcGIS Server Manager. The resource utilization (RAM and CPU) of the VM is under 30%. OS of the VMs is Window 10 Enterprises
As part of our troubleshooting efforts, we observed a significant improvement in response time after clearing the following items on the deployed VMs using the Disk Cleanup utility. A snapshot for the same is given below for your reference:
Thumbnails, Temporary files, DirectX cache, Delivery optimization files

Could you please assist us in resolving the issue.
Thanks & regards,
Kristofer