I recently got a new work computer, and made the switch to Windows 10 64-bit. My ArcMap is version 10.3
I've noticed that if I have an mxd open for awhile, it tends to, for lack of a better phrase, screw up connections to any and all file geodatabase. It does not "lose" the connection, I can still access feature properties, etc, and it does not give the "red exclamations." However, if I browse source connections, and retype the path, it still does not draw and will give this error:
One or more layers failed to draw:
FDO error: 0
General function failure
[File GDB layer name]: General function failure