My university recently purchased AppsAnywhere and we have noticed unique behavior while attempting to run Arc Pro through it. The splash screen will appear and then Pro will immediately crash. The only solution is to right click on the shortcut to Pro and run it as an administrator. The really odd thing is that this works even if the account is not an administrator on the machine. After discovering this with AppsAnywhere, I tried RDP by itself and ran into the same problems. This affects at least versions 2.4, 2.5, 2.6 and the minor updates within.
Has anyone ran into this before? Is it an issue with Pro, RDP in general, or AppsAnywhere? It does not occur with ArcMap 10.5.1 or later.