Hello,
I am publishing this question in the Portal location as I did not see a location specifically catering to the Web Adaptor. I have installed web adaptor 10.5 on a server and configured both Portal for ArcGIS and ArcGIS for Server with different web adaptor names. Both Portal and ArcGIS Server are separate servers. I am able to use Internet Explorer and access the websites for Portal and ArcGIS Server through the web adaptor, however when I use Google Chrome to accomplish the same task I get the error "This site can't be reached: ERR_CONNECTION_RESET". Has anyone encountered this before? While IE is my company's recommended browser, we will have several users that will use Chrome.