I have an issue loading data into an Enterprise geodatabase using 10.5. It was working while ESRI was here but now all of my 10.5 Desktops hang when trying to load data but my 10.4.1 can load with no problem. I have 3 Enterprise GDBs setup all with proper connections setup and they all have the same issue.
Your question does not mention the issues\errors you are facing.
Thanks for your quick interest.