Use Map Series to create multiple maps of same extent, query multiple layers

[SH_DH]

I have a workflow for a type of project where a set of maps needs to be created based on different attribute values. This applies to multiple point/polygon layers within the map.  For example, create 10 maps of the same extent using the same 3 layers, simply updating definition queries to change which features are displayed.

I'm new to Map Series, and they seem to get me close, however they also seem to change extent/zoom to each feature as the definition query changes. I also don't see that you can apply these definition query updates to multiple layers.  Is there a solution for what I'm looking for within map series or another feature within Pro?

Alternatively I can build a script with arcpy.mapping, just wanted to make sure I'm not missing anything with the built in functionality. Thanks!

[AubriKinghorn · Accepted solution]

You can't do this in the default functionality, but you can definitely script it. This thematic map series sample script is a similar example (although it turns layers on/off instead of changing the definition query) and may be a helpful starting point https://www.arcgis.com/home/item.html?id=eba53351ceb84b58b505dec5272e526c 

[SH_DH]

thanks!