I have found that when I mosaic raster images (orthos), that the final mosaic product does not display properly. It will only fully display when zoomed in. But as I zoom out, 'tiles' from the mosaic start to disappear. Zoomed out, the mosaic is not usable as it only partially draws. My mosaic consists of ~20 orthos and I've reduced the output resolution.
I'm wondering if this could be a hardware limitation on my end? I've run the tech check and I think all is ok (see attached).
My first thought its that you can play with the field "MaxPS" by assigning a large number depending on your scale, to draw all the rasters Mosaic Dataset Properties
On the other hand, I have had problems exporting the Mosaics but haven't heard from anybody. Here is the post
So it seems the problem was saving the mosaic within a geodatabase. If I save the mosaic as an uncompressed tif, then there are no rendering issues at any scale.