I encountered same problem.Because, I have already added add-in to ArcGIS Explorer. Error message said that the assenbly '***' has already loaded from a different location. When I delete the add-in that is already added, I can load add-in.Your computer already has add-in? Please look at the following on your computer.C:\Documents and Settings\<User Name>\Application Data\ESRI\arcgis explorer\AddIns
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