I was using the older Human Geography basemap in ArcProfanity 2.4.2 because I like the way it looks. I wanted to clip some of the layers to the extent of a definition query I have set on one of our municipalities. I wanted to configure the clip to exclude certain layers (see screenshot below) but none of my layers, which are clearly visible in the layer list, show up as options.
I thought, "ok, well that sucks, but no big deal. I'll just remove the Human Geography map and use a different one."
I added the light gray basemap and tried to set my clipping exclusion (same screenshot). No dice. I've saved and closed the map, reopened it. Removed layers and added them back in. At this point the map in the project is unusable and I pretty much have to start over...
*much profanity ensues*
I think this issue might be related to this topic: