In Drone2Map I have created my .las point cloud from imagery, but cannot figure out how to calculate volume with it. I have 3D Analyst, but when I select the layer in D2M the various Measure tools are not enabled.
I think you may be mixing help topics between Versions 1.3 and 2.0. Volume measurement changed in 2.0, so it's based on the DSM (created as a 2D product) instead of the point cloud. Also you do not need 3D analyst with Drone2Map 2.0.
See help here Perform measurements—ArcGIS Help | ArcGIS and when navigating help, be sure you don't end up back in the version 1.3 topics
Retrieving data ...