Did you try shutting down all instances of ArcGIS Pro and opening one again to see if it worked then? (Or, maybe even a PC restart?)
Yes, at least ten times.
I don't suppose you have another mouse to rule that out
I do and it didn't make any difference. The mouse wheel works fine in other applications.
I can see nothing in the project options under Navigation or anything.
My 'wheel' works (it is actually just a strip between the two buttons which functions like a wheel)
with your exact settings.
Nothing changed in my settings from when the mouse wheel worked to zoom until now. It is a great, but annoying, mystery.
Keith,
Could you perform a Repair Install on ArcGIS Pro? I don't know if that would help or not but I don't think it would hurt anything.
I can't find a repair install option.
In the control panel on Windows (I'm using 10), find the programs and features, click on ArcGIS Pro, and then click on Uninstall/Change.
After that, a box will pop up, from there you can click on Repair: