i know that my question is a little bit strange, but i would like to have a clear answer if it is possible to make map layouts having the travel direction instead of the North up using ArcMap.
You can rotate each data frame to whichever direction you want. Right-Click on the data frame and select Properties...
Select the General Tab and type the rotation you want (I typed in 180 to turn it so South is at the top of the frame)
What Laura said works. Another way is to add the Data Frame Tools Toolbar
Go to Customize --> Toolbars --> Data Frame Tools
Here, you can type in the rotation, or you can use the tool to the left (the Rotate tool) and physically drag the map around to the rotation you like.
When you go to the layout view and add a North Arrow, the arrow will reflect where North is supposed to be.
I've never used the Data Frames Toolbar. That's way faster than my method!
Retrieving data ...