ArcGIS doesn't open, showing "XML Parser Initialization Failed"

Discussion created by jacksonlord on Aug 4, 2010
Latest reply on Aug 24, 2012 by lauracockrell
ArcGIS (Map and Catalog) hangs while starting and never opens. I'm periodically getting this error, particularly when I first start up the machine. The error has an ArcGIS heading.

How do I fix? Hopefully don't have to re-install

ArcGIS 10.0, Build 2414, ArcView Single license.