Esri ArcGIS unable to execute print when passing F5 LTM

[Ryan_EricSia]

I am having a problem with one of our web server that serves Map services with PRINT to PDF functionality. All services are good when the web server bypasses F5, but when it passes through F5 on a Virtual Server with standard type VS (using default TCP profile, inserted SSL client and server) PRINT to PDF gets an error and it doesn't work. Maybe you guys have experienced this or may share inputs. Thank you!

Our setup is:

ArcGIS Server <----- Web Server (web adaptor to FQDN) <----- F5 BIGIP LTM <------- ISP Router <-------- INTERNET