I am trying to calculate the driving distances between certain patient address locations and a specific hospital facility that each patient visits. Is there any way to utilize OD cost matrix to perform this analysis? Rather than finding driving distances from all origins to all destinations, I am trying to find the driving distance from one specific origin to one specific destination. There are nearly 2000 patients who travel to 20 different facilities. I have tried to use the route analysis as described here http://forums.arcgis.com/threads/30795-calculating-driving-distances, however, the output seems to be incorrect. Could someone please shed some light on the best way to approach this. Thanks.