I did as you suggested and it opened right up with no data saved.
However, when I opened up my previous workspace and disconnected the GIS Service layers, saved it out, cleared the cache, and tried to open it without the GIS Service layers. It took 12 minutes to open. Each time I try to open this same Map it takes longer and longer. I have also tried deleting and rebuilding it and the same things are happening.
The only content added includes the following:shapefiles, ArcGIS Layers, and some raster data. This happens on multiple computers.