Assuming you don't care about extra PCI lanes, ECC memory etc. a high-end core series is usually better than any workstation class Xeon in Pro due to the inevitable single thread bottlenecks. That said, these 2 tools might actually use threads efficiently so it's hard to tell without proper benchmarking. If you have the budget and time then build both, run your standard workflows on both and refund whatever loses. You should also consider AMD's standard chips over Intel, the high-end Core chips have a bad habit of destroying themselves and the X3D chips obliterate anything that's memory bottlenecked (i.e. almost everything your computer does).
