Solved! Go to Solution.
You should be able to do it. See: http://resources.arcgis.com/en/help/main/10.1/index.html#/Adding_a_server_directory_in_Manager/01540...
This may be helpful too: http://resources.arcgis.com/en/help/main/10.1/index.html#/Adding_a_server_directory_in_ArcGIS_for_De...
Then what I would also do is run the 10.1 Configure ArcGIS Server account. Point the arcgisserver\directories to the new drive.
What about this location: C:\arcgisserver\directories\arcgissystem\arcgisinput This partition takes almost the same GB size as arcgiscatch folder. Can I move it to another partition without reinstalling arcgisserver?