Definitely, and there is probably more than one way to go about doing this.
One, draw two lines and set them both to one-way pairs. You might draw one line first, select the line and copy it for symmetry. This method would work best if using on/off ramps. This is probably the best way.
Two, if your divided highway is very limited access and/or has rural crossing intersections , you could use one street and set the width to something really wide to accommodate all lanes and add a grass boulevard.
You could also use the ESRI fence code in the sidewalks space to create different safety barriers.
I would start with an existing code, some have a little freeway structure already like the complete streets code, and then see if you need more customization from there.
