If you want to use Python 32Bit, set PYTHONHOME to the appropriate python.exe-Path: >set PYTHONHOME=C:\Python27\ArcGIS10.2 Installing Modules: Change to the unpacked Module-Code: eg: >cd c:\Temp\Python27\setuptools-5.4.2 >C:\Python27\ArcGIS10.2\python.exe setup.py install When installing with "pip install Module", run pip 32Bit: C:\Python27\ArcGIS10.2\Scripts\pip.exe install Module Running Python 32Bit: >C:\Python27\ArcGIS10.2\python.exe yourcode.py When you want to use Python 64Bit, set PYTHONHOME to the appropriate python.exe-Path: >set PYTHONHOME=C:\Python27\ArcGISx6410.2 Installing Modules: Change to the unpacked Module-Code: eg: >cd c:\Temp\Python27\setuptools-5.4.2 >C:\Python27\ArcGISx6410.2\python.exe setup.py install When installing with "pip install Module", run pip 64Bit: C:\Python27\ArcGISx6410.2\Scripts\pip.exe install Module Running Python 64Bit: >C:\Python27\ArcGISx6410.2\python.exe yourcode.py Always install all Python-Modules in 32 and 64Bit:
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